Having been able to rest the majority of their first team at the weekend, the Catalans should be much fresher and their daunting home form in this competition means it is extremely difficult to oppose them.
Valvderde's men can be backed at 2.21 to win with a -1.75 Asian handicap and this looks like an excellent option for a side as good as Barcelona playing at home.
Visitors fell 3-0 to Barcelona on Tuesday evening at Camp Nou in the reverse fixture of the Champions League quarter-final. Such tough loss may affect their confidence coming into this super important fixture against Everton.
Overall, the Red Devils were struggling badly to pick up results on travels lately. They lost four on the spin away from home in all competitions, a streak which includes two consecutive defeats to Wolverhampton Wanderers (in both FA Cup and Premier League).
On the other side, Everton kept their net untouched in each of last three home outings in the league. They won two and drew one in the process even though the opposition came in the likes of Liverpool, Chelsea and Arsenal. The value is thus massive with Everton or Draw